Description

3-o-Acetyl-6-O-Benzoyl-5-o-(Methylsulfonyl)-1,2-o-Isopropylidene-α-D-Glucofuranose CAS NO 102029-58-3 is a sophisticated, multi-protected carbohydrate derivative serving as a critical chiral building block and synthetic intermediate. Its value lies in its precisely positioned protecting groups, which enable selective deprotection and controlled functionalization for complex molecular assembly. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for the synthesis of nucleoside analogs, antiviral agents, and other bioactive molecules where stereochemical control is paramount.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of nucleoside analogs and antiviral drugs.
• Carbohydrate Chemistry Research: A versatile building block for constructing complex oligosaccharides and glycoconjugates.
• Fine Chemical Synthesis: Used in the preparation of specialized reagents and catalysts requiring specific sugar scaffolds.
• Glycobiology Studies: Serves as a precursor for labeled or modified sugars used in metabolic pathway analysis.
• Process Development: Employed in route scouting and optimization for the commercial production of sugar-based active pharmaceutical ingredients (APIs).
• Academic & Industrial R&D: Fundamental material for exploring new synthetic methodologies in organic and medicinal chemistry.

Basic Information

Product Name	3-o-Acetyl-6-O-Benzoyl-5-o-(Methylsulfonyl)-1,2-o-Isopropylidene-α-D-Glucofuranose
CAS No.	102029-58-3
Molecular Formula	C20H24O9S
Molecular Weight	440.46 g/mol
Synonyms	1,2-O-Isopropylidene-3-O-acetyl-6-O-benzoyl-5-O-(methylsulfonyl)-α-D-glucofuranose; 5-O-Mesyl-1,2:5,6-di-O-isopropylidene-3-O-acetyl-α-D-glucofuranose (related protected form); 3-Acetyl-6-benzoyl-5-mesyl-1,2-isopropylidene-α-D-glucofuranose; 5-O-(Methylsulfonyl)-1,2-O-isopropylidene-3-O-acetyl-6-O-benzoyl-α-D-glucofuranose; Protected D-Glucofuranose Derivative; CAS 102029-58-3; α-D-Glucofuranose, 3-acetyl-6-benzoyl-5-(methylsulfonyl)-1,2-O-(1-methylethylidene)-
EINECS	Contact for details

Quality Control

Our 3-o-Acetyl-6-O-Benzoyl-5-o-(Methylsulfonyl)-1,2-o-Isopropylidene-α-D-Glucofuranose is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Specific Rotation [α]²⁰D	Contact for details
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.