Description

8,8,8-Trifluoro-7-Hydroxy-7-(Trifluoromethyl)-2,5-Octanedione is a high-value fluorinated diketone building block, distinguished by its unique geminal trifluoromethyl and hydroxyl groups. This compound is critical for the synthesis of advanced materials and pharmaceuticals due to its ability to introduce significant lipophilicity and metabolic stability. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where fluorine atoms enhance biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized fluorinated ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Advanced Material Research: Employed in the synthesis of fluorinated polymers and coatings that require specific surface properties, chemical resistance, and low surface energy.
• Fluorine Chemistry Research: An essential building block in academic and industrial labs for studying the effects of polyfluorination on molecular conformation and reactivity.
• Fine Chemical Production: Utilized in multi-step syntheses to produce complex, high-value fluorinated fine chemicals for various industrial applications.

Basic Information

Product Name	8,8,8-Trifluoro-7-Hydroxy-7-(Trifluoromethyl)-2,5-Octanedione
CAS No.	101858-31-5
Molecular Formula	C9H9F6O3
Molecular Weight	270.16 g/mol
Synonyms	1,1,1-Trifluoro-2-hydroxy-2-(trifluoromethyl)-5,8-octanedione; 2,5-Octanedione, 8,8,8-trifluoro-7-hydroxy-7-(trifluoromethyl)-; 7-Hydroxy-7-(trifluoromethyl)-8,8,8-trifluoro-2,5-octanedione; 1,1,1,7,7,7-Hexafluoro-2-hydroxy-2-methyl-3,6-octanedione; Hexafluorinated β-hydroxy diketone; Fluorinated hydroxy diketone intermediate
EINECS	Contact for details

Quality Control

Our 8,8,8-Trifluoro-7-Hydroxy-7-(Trifluoromethyl)-2,5-Octanedione is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in its original packaging to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.