Description

1-Bromo-2,3-Dimethyl-4-Nitrobenzene is a versatile halogenated aromatic nitro compound that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring bromine and nitro substituents on a dimethylbenzene backbone, makes it an essential intermediate for creating complex molecules. This compound is primarily sought after by research institutions and chemical manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in the development of active pharmaceutical ingredients (APIs) with specific halogenated aromatic motifs.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides, where its bromo-nitro aromatic structure contributes to biological activity.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Manufacturing: Acts as an intermediate for synthesizing complex azo dyes and other high-performance colorants.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, and Buchwald-Hartwig amination, enabling carbon-carbon and carbon-heteroatom bond formation.
• Organic Synthesis Reagent: Employed in academic and industrial R&D labs for constructing complex molecular architectures due to its reactivity as both an electrophile and a potential directing group.

Basic Information

Product Name	1-Bromo-2,3-Dimethyl-4-Nitrobenzene
CAS No.	101421-63-0
Molecular Formula	C8H8BrNO2
Molecular Weight	230.06 g/mol
Synonyms	2,3-Dimethyl-1-bromo-4-nitrobenzene; 4-Nitro-1-bromo-2,3-dimethylbenzene; 1-Bromo-2,3-dimethyl-4-nitrobenzene; 2-Bromo-1,4-dimethyl-3-nitrobenzene; Benzene, 1-bromo-2,3-dimethyl-4-nitro-; 3-Nitro-4-bromo-o-xylene
EINECS	Contact for details

Quality Control

Our 1-Bromo-2,3-Dimethyl-4-Nitrobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.