Description

3-Penten-2-One, 5,5,5-Trifluoro-, (3E)- (9Ci) is a high-purity, fluorinated α,β-unsaturated ketone, serving as a versatile and valuable building block in advanced organic synthesis. Its unique structure, featuring a trifluoromethyl group and an enone moiety, makes it a critical intermediate for introducing fluorinated segments into target molecules, which can dramatically alter their physical, chemical, and biological properties. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to enhance compound stability, bioavailability, and lipophilicity.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated active pharmaceutical ingredients (APIs) and drug candidates, leveraging the "fluorine effect" to improve metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in creating novel fluorinated pesticides, herbicides, and fungicides, where the trifluoromethyl group can increase biological activity and environmental persistence.
• Advanced Material Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers, coatings, and liquid crystals with enhanced chemical resistance and unique optical properties.
• Organic Synthesis Reagent: Employed in Michael additions, cycloadditions, and other carbon-carbon bond-forming reactions to construct complex, fluorinated molecular architectures.
• Fluorine Chemistry Research: A valuable reference standard and starting material in academic and industrial R&D focused on organofluorine chemistry and methodology development.

Basic Information

Product Name	3-Penten-2-One, 5,5,5-Trifluoro-, (3E)- (9Ci)
CAS No.	101395-81-7
Molecular Formula	C5H5F3O
Molecular Weight	138.09 g/mol
Synonyms	(3E)-5,5,5-Trifluoro-3-penten-2-one; 5,5,5-Trifluoro-3-penten-2-one, (3E)-; (E)-5,5,5-Trifluoropent-3-en-2-one; 5,5,5-Trifluoro-3-penten-2-one; Trifluoromethyl vinyl ketone derivative; 1,1,1-Trifluoro-4-penten-3-one; (E)-1,1,1-Trifluoro-4-penten-3-one
EINECS	Contact for details

Quality Control

Our 3-Penten-2-One, 5,5,5-Trifluoro-, (3E)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, assay, and impurity profiles to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases, reducing agents, and sources of ignition. For long-term storage, consider maintaining under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Specific Isomer Content (GC)	≥ 95.0% (E)-isomer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.