Description

4-Chloro-3-Methyl-Pyridazine.Hcl is a high-purity heterocyclic building block essential for advanced organic synthesis. This compound matters as a versatile intermediate for constructing complex molecular architectures in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and novel materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the pyridazine core's bioactivity.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and lead optimization.
• Material Science Precursor: Potential intermediate in the synthesis of specialty polymers, ligands for catalysis, and organic electronic materials.
• Contract Manufacturing (CMO): Supplied to custom synthesis organizations for scale-up and production of client-specific target molecules.
• Academic Research: Utilized in university and institutional labs for methodological development and exploratory synthesis projects.

Basic Information

Product Name	4-Chloro-3-Methyl-Pyridazine.Hcl
CAS No.	101346-01-4
Molecular Formula	C5H6ClN2•HCl
Molecular Weight	165.03 g/mol (Free base: 128.56 g/mol)
Synonyms	4-Chloro-3-methylpyridazine hydrochloride; 3-Methyl-4-chloropyridazine hydrochloride; 4-Chloro-3-methyl-1,2-diazine hydrochloride; 4-Chloro-3-methylpyridazine HCl; 4-Chloro-3-methylpyridazine monohydrochloride; 101346-01-4; 4-Chloro-3-methyl-1,2-diazine HCl
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-Methyl-Pyridazine.Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.