Description

(2-Chloro-6-Nitrophenyl)Methanamine is a versatile aromatic amine building block characterized by its chloro and nitro substituents, which make it a key intermediate in advanced organic synthesis. Its primary value lies in its ability to undergo further functionalization, enabling the construction of complex molecules for research and industrial applications. This compound is essential for pharmaceutical chemists, agrochemical researchers, and material scientists developing active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a substituted aniline core.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and insecticides, where its halogen and nitro groups are pivotal for bioactivity.
• Dye and Pigment Manufacturing: Acts as a key intermediate for producing azo dyes and other complex colorants.
• Material Science Research: Employed in the creation of novel polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: A valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Cross-Coupling Reactions: Functions as a substrate in palladium-catalyzed reactions like Buchwald-Hartwig amination for creating C-N bonds.

Basic Information

Product Name	(2-Chloro-6-Nitrophenyl)Methanamine
CAS No.	101252-73-7
Molecular Formula	C7H7ClN2O2
Molecular Weight	186.60 g/mol
Synonyms	1-(2-Chloro-6-nitrophenyl)methanamine; (2-Chloro-6-nitrobenzyl)amine; 2-Chloro-6-nitrobenzylamine; α-Amino-2-chloro-6-nitrotoluene; Benzenemethanamine, 2-chloro-6-nitro-; 2-Chloro-6-nitrobenzenemethanamine; 2-Chloro-6-nitro-α-toluidine
EINECS	Contact for details

Quality Control

Every batch of (2-Chloro-6-Nitrophenyl)Methanamine is produced and tested under a strict quality management system to ensure consistency and reliability for your synthesis. We provide comprehensive Certificates of Analysis (COA) that detail purity, identity, and impurity profiles, supporting your regulatory and R&D requirements. Our quality commitment ensures the material meets the high standards demanded for pharmaceutical and advanced chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under anhydrous conditions to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%
Single Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.