Description

A-Amino-4-Hydroxycyclohexaneacetic Acid is a functionalized cyclohexane derivative that serves as a versatile chiral building block in advanced organic synthesis. This compound matters for its ability to introduce both amino and carboxylic acid functionalities in a rigid, stereodefined cyclohexane scaffold, enabling the construction of complex molecular architectures. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for applications such as peptidomimetics, active pharmaceutical ingredient (API) intermediates, and ligand synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel drug candidates, particularly in central nervous system (CNS) and metabolic disease research.
• Peptidomimetic Scaffold: Used to design and synthesize conformationally restricted peptide analogs to enhance metabolic stability and receptor selectivity.
• Agrochemical Synthesis: Serves as a precursor for creating novel herbicides or fungicides with specific stereochemical requirements.
• Catalyst & Ligand Development: Employed in the synthesis of chiral ligands for asymmetric catalysis, such as in hydrogenation or hydroxylation reactions.
• Academic & Industrial Research: A valuable tool compound for methodological studies in organic chemistry and medicinal chemistry programs.
• Custom Synthesis Building Block: Provides a foundational structure for contract research organizations (CROs) and CDMOs to build custom molecules for clients.

Basic Information

Product Name	A-Amino-4-Hydroxycyclohexaneacetic Acid
CAS No.	101252-25-9
Molecular Formula	C8H15NO3
Molecular Weight	173.21 g/mol
Synonyms	2-Amino-2-(4-hydroxycyclohexyl)acetic acid; (4-Hydroxycyclohexyl)glycine; 4-Hydroxycyclohexylglycine; 2-Amino-2-(trans-4-hydroxycyclohexyl)acetic acid; trans-4-Hydroxycyclohexylglycine; Cyclohexaneacetic acid, α-amino-4-hydroxy-; (1r,4r)-4-(Aminomethyl)cyclohexanol-1-acetic acid (stereoisomer); A-Amino-4-hydroxycyclohexaneacetic acid
EINECS	Contact for details

Quality Control

Our A-Amino-4-Hydroxycyclohexaneacetic Acid is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and process development. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data (including HPLC, NMR, and MS) are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Specific Rotation	Contact for details
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.