Description

Bicyclo[2.2.1]Hept-2-Ene-7-Carboxylic Acid, 5-Oxo-, (1S-Syn)- (9Ci) is a high-purity, stereochemically defined bicyclic compound that serves as a critical chiral building block and synthetic intermediate. Its unique strained ring structure and functional groups make it valuable for constructing complex molecular architectures with precise spatial orientation. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of novel drug candidates, especially in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Asymmetric Catalysis: Used as a ligand precursor or a scaffold for developing new chiral catalysts and auxiliaries.
• Fine Chemical Synthesis: Building block for the production of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & R&D: Valuable reagent for methodological studies in organic synthesis, including cycloaddition reactions and ring-opening polymerizations.
• Material Science: Potential monomer for creating polymers with unique thermal and mechanical properties derived from the norbornene core.

Basic Information

Product Name	Bicyclo[2.2.1]Hept-2-Ene-7-Carboxylic Acid, 5-Oxo-, (1S-Syn)- (9Ci)
CAS No.	101223-39-6
Molecular Formula	C9H10O3
Molecular Weight	166.17 g/mol
Synonyms	(1S,4R)-4,7-Dihydro-4,7-methanoisobenzofuran-1(3H)-one-5-carboxylic acid; 5-Oxo-4,7-methanoisobenzofuran-1(3H)-carboxylic acid, (1S,4R)-; (1S,4R)-1,3,3a,4,7,7a-Hexahydro-4,7-methanoisobenzofuran-1-carboxylic acid-5-one; endo-5-Norbornene-2-carboxylic-3-one acid; 5-Oxonorborn-2-ene-endo-7-carboxylic acid; (1S,4R)-5-Oxo-1,3,3a,4,7,7a-hexahydro-4,7-methanoisobenzofuran-1-carboxylic acid
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.1]Hept-2-Ene-7-Carboxylic Acid, 5-Oxo-, (1S-Syn)- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure high chemical and stereochemical purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.