Description

1-(4-Acetylphenyl)-3-(4-Chlorophenyl)Urea is a high-purity, diaryl urea derivative with significant potential as a key synthetic intermediate in advanced organic chemistry. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for lead optimization and process chemistry.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of kinase inhibitors and other small molecule drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in the development of novel herbicides and plant growth regulators, leveraging its urea core structure.
• Chemical Biology Probe: Serves as a scaffold for creating molecular probes to study enzyme function and protein-protein interactions.
• Material Science: Investigated as a monomer or precursor for the synthesis of specialty polymers and advanced organic materials.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the discovery of new chemical reactions.
• Custom Synthesis: A starting point for the tailored synthesis of more complex, customer-specific urea derivatives.

Basic Information

Item	Details
Product Name	1-(4-Acetylphenyl)-3-(4-Chlorophenyl)Urea
CAS No.	101095-67-4
Molecular Formula	C15H13ClN2O2
Molecular Weight	288.73 g/mol
Synonyms	N-(4-Acetylphenyl)-N'-(4-chlorophenyl)urea; 1-(4-Acetylphenyl)-3-(4-chlorophenyl)urea; 4-Acetylphenyl 4-chlorophenylurea; (4-Acetylphenyl)-(4-chlorophenyl)urea; Urea, N-(4-acetylphenyl)-N'-(4-chlorophenyl)-; Urea, 1-(4-acetylphenyl)-3-(4-chlorophenyl)-; 4-Chloro-N-[(4-acetylphenyl)carbamoyl]aniline
EINECS	Contact for details

Quality Control

Every batch of 1-(4-Acetylphenyl)-3-(4-Chlorophenyl)Urea is produced under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment, confirming compliance with agreed specifications for research and commercial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.