Description

2H-Pyran-3-Ol, Tetrahydro-, (R)- is a high-purity chiral building block and intermediate of significant interest in advanced organic synthesis. Its defined stereochemistry and functionalized pyran ring structure make it a valuable precursor for the development of pharmaceuticals, agrochemicals, and specialty materials. This compound is particularly sought after by research and development teams in the fine chemical, pharmaceutical, and flavor & fragrance industries for creating complex, optically active molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in antiviral, cardiovascular, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced, stereospecific pesticides and herbicides where biological activity is enantiomer-dependent.
• Flavor & Fragrance Ingredient: Serves as a precursor for synthetic routes to complex, naturally-derived flavor molecules and aroma chemicals.
• Asymmetric Catalysis Ligand Precursor: Its structure can be modified to create novel chiral ligands for asymmetric hydrogenation and other catalytic processes.
• Academic & Industrial Research: A valuable reagent for methodological development in organic chemistry and for exploring new chemical spaces in medicinal chemistry.
• Specialty Polymer Monomer: Potential use as a building block for synthesizing novel polymers with specific optical or material properties.

Basic Information

Product Name	2H-Pyran-3-Ol, Tetrahydro-, (R)-
CAS No.	100937-76-6
Molecular Formula	C5H10O2
Molecular Weight	102.13 g/mol
Synonyms	(R)-Tetrahydro-2H-pyran-3-ol; (3R)-3-Hydroxytetrahydropyran; (R)-3-Hydroxytetrahydropyran; (R)-Tetrahydropyran-3-ol; (R)-THP-3-ol; Tetrahydro-2H-pyran-3-ol, (R)-; (R)-3-Hydroxyoxane; (R)-Oxan-3-ol
EINECS	Contact for details

Quality Control

Our production of (R)-Tetrahydro-2H-pyran-3-ol adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized using advanced analytical techniques including chiral HPLC, GC, and NMR to confirm identity, enantiomeric excess (ee), and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed after opening to prevent degradation due to moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.