Description

3-[(2R,3R,4R,5R)-3,4-Dihydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]-1-(2-Meth Yl-4-Oxo-Pentan-2-Yl)Thiourea is a specialized thiourea derivative with a complex sugar-like (oxolan-2-yl) backbone. This compound is significant for its role as a key synthetic intermediate and building block in advanced organic synthesis, particularly in the development of nucleoside analogs and other bioactive molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel nucleoside analogs and other potential active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a sophisticated building block for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Biochemical Research: Employed in studies exploring enzyme inhibition, carbohydrate-protein interactions, and other biochemical pathways.
• Process Chemistry Development: Utilized in route scouting and optimization for the scalable production of complex organic molecules.
• Academic Research: A valuable reagent for universities and research institutes focusing on organic synthesis methodology and heterocyclic chemistry.

Basic Information

Product Name	3-[(2R,3R,4R,5R)-3,4-Dihydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]-1-(2-Meth Yl-4-Oxo-Pentan-2-Yl)Thiourea
CAS No.	100551-67-5
Molecular Formula	C12H22N2O5S
Molecular Weight	306.38 g/mol
Synonyms	1-(1,1-Dimethyl-3-oxobutyl)-3-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]thiourea; 1-(2-Methyl-4-oxopentan-2-yl)-3-β-D-ribofuranosylthiourea; β-D-Ribofuranosyl-1-(1,1-dimethyl-3-oxobutyl)thiourea; Thiourea, N-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydro-2-furanyl]-N'-(1,1-dimethyl-3-oxobutyl)-; Ribose thiourea derivative; (2R,3R,4R,5R)-2-({[(1,1-Dimethyl-3-oxobutyl)amino]carbonothioyl}amino)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
EINECS	Contact for details

Quality Control

Our 3-[(2R,3R,4R,5R)-3,4-Dihydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]-1-(2-Meth Yl-4-Oxo-Pentan-2-Yl)Thiourea is produced under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and structural identity. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and relevant research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.