Description

Ethyl (2R,5S)-5-Hydroxyoxane-2-Carboxylate is a high-purity chiral building block and pharmaceutical intermediate of significant synthetic value. This compound matters for its role in the stereoselective synthesis of complex molecules, offering a defined stereochemistry that is crucial for developing active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors seeking to incorporate specific stereocenters into their target compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, particularly in antiviral, antibacterial, and central nervous system (CNS) drug candidates.
• Asymmetric Synthesis: Used as a starting material or reagent in asymmetric catalytic reactions and multi-step organic syntheses to introduce the (2R,5S) stereochemistry.
• Agrochemical Research: Serves as a building block for creating chiral active ingredients in herbicides, fungicides, and insecticides where specific stereoisomers exhibit enhanced biological activity.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, fragrances, and advanced polymers requiring high enantiomeric purity.
• Academic & Contract Research: A valuable reagent for methodological development in academic laboratories and contract research organizations (CROs) focused on synthetic organic chemistry.

Basic Information

Product Name	Ethyl (2R,5S)-5-Hydroxyoxane-2-Carboxylate
CAS No.	100514-05-4
Molecular Formula	C8H14O4
Molecular Weight	174.19 g/mol
Synonyms	Ethyl (2R,5S)-5-Hydroxytetrahydropyran-2-carboxylate; (2R,5S)-5-Hydroxy-tetrahydropyran-2-carboxylic Acid Ethyl Ester; Ethyl 5-Hydroxyoxane-2-carboxylate; Ethyl 5-Hydroxytetrahydropyran-2-carboxylate; (2R,5S)-Ethyl 5-Hydroxytetrahydropyran-2-carboxylate; (2R,5S)-5-Hydroxyoxane-2-carboxylic Acid Ethyl Ester; Tetrahydropyran-2-carboxylic Acid, 5-Hydroxy-, Ethyl Ester, (2R,5S)-
EINECS	Contact for details

Quality Control

Our Ethyl (2R,5S)-5-Hydroxyoxane-2-Carboxylate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.