Description

Ethyl cis-5-Hydroxy-Tetrahydro-Pyran-2-Carboxylate is a high-purity chiral building block and pharmaceutical intermediate of significant synthetic value. This compound is essential for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals due to its functionalized tetrahydro-2H-pyran ring structure. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for advanced synthesis and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its stereochemistry for enhanced biological activity.
• Fine Chemical Production: Serves as a versatile precursor for creating specialty chemicals, flavors, and fragrances requiring specific stereochemical configurations.
• Academic & Industrial Research: A valuable reagent in medicinal chemistry and organic synthesis research for constructing oxygen-containing heterocycles and exploring new synthetic methodologies.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial production, where consistent quality is critical.

Basic Information

Product Name	Ethyl cis-5-Hydroxy-Tetrahydro-Pyran-2-Carboxylate
CAS No.	100514-02-1
Molecular Formula	C8H14O4
Molecular Weight	174.19 g/mol
Synonyms	Ethyl (cis)-5-Hydroxytetrahydro-2H-pyran-2-carboxylate; Ethyl 5-Hydroxytetrahydro-2H-pyran-2-carboxylate, cis-; cis-5-Hydroxy-tetrahydro-pyran-2-carboxylic acid ethyl ester; 2H-Pyran-2-carboxylic acid, 5-hydroxy-tetrahydro-, ethyl ester, cis-; Ethyl cis-5-hydroxytetrahydro-2H-pyran-2-carboxylate; Ethyl cis-5-hydroxytetrahydropyran-2-carboxylate; cis-Ethyl 5-hydroxytetrahydro-2H-pyran-2-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl cis-5-Hydroxy-Tetrahydro-Pyran-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for prolonged operations to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (cis-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.