Description

2-{[(4-Bromophenyl)Amino]Methyl}-4-Chlorophenol is a specialized halogenated phenolic compound with a unique bifunctional structure, serving as a valuable intermediate in advanced organic synthesis. Its molecular architecture, featuring both bromo and chloro substituents on aromatic rings linked by an aminomethyl bridge, makes it a versatile building block for constructing complex molecules with tailored properties. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing antimicrobial activity.
• Agrochemical Synthesis: Building block for developing new-generation herbicides, fungicides, and plant growth regulators that require specific halogenated phenolic cores.
• Material Science Research: Used in the development of specialty polymers, liquid crystals, or organic electronic materials due to its rigid, multi-halogenated structure.
• Chemical Biology Probes: Serves as a scaffold for creating fluorescent tags or molecular probes for studying biological pathways and protein interactions.
• Dye and Pigment Intermediate: Potential starting material for synthesizing advanced colorants and pigments with enhanced lightfastness and chemical stability.
• Cross-coupling Reactions: Valuable substrate in palladium-catalyzed reactions (e.g., Suzuki, Buchwald-Hartwig) for creating complex biaryl and amine-linked structures.

Basic Information

Product Name	2-{[(4-Bromophenyl)Amino]Methyl}-4-Chlorophenol
CAS No.	100374-80-9
Molecular Formula	C13H11BrClNO
Molecular Weight	312.59 g/mol
Synonyms	4-Chloro-2-[(4-bromophenyl)aminomethyl]phenol; 2-[(4-Bromoanilino)methyl]-4-chlorophenol; Phenol, 2-[[(4-bromophenyl)amino]methyl]-4-chloro-; 2-((4-Bromophenylamino)methyl)-4-chlorophenol; 4-Chloro-2-((4-bromophenylamino)methyl)phenol; 100374-80-9; 2-[(4-Bromophenylamino)methyl]-4-chlorophenol
EINECS	Contact for details

Quality Control

Our 2-{[(4-Bromophenyl)Amino]Methyl}-4-Chlorophenol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and scale-up applications. We provide comprehensive analytical data including HPLC purity, NMR confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is supplied with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.