Description

3-Amino-5-Bromophenol is a versatile brominated aniline derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both an amino and a phenolic hydroxyl group, makes it a valuable intermediate for constructing complex molecular architectures. This compound is primarily utilized in the pharmaceutical, agrochemical, and specialty dye industries for the synthesis of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and as a scaffold for kinase inhibitors.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the bromine atom and amino group facilitate the introduction of specific bioactive moieties.
• Dye and Pigment Manufacturing: Serves as a coupling agent for the creation of azo dyes and high-performance pigments, contributing to color fastness and thermal stability.
• Polymer Chemistry: Acts as a monomer or chain modifier in the synthesis of specialty polymers, such as polyimides and epoxy resins, enhancing material properties.
• Ligand and Catalyst Development: Employed in the design of chelating ligands for metal catalysis and in organocatalysis research.
• Research and Development: A valuable reagent in academic and industrial R&D for exploring new chemical entities and reaction pathways.

Basic Information

Product Name	3-Amino-5-Bromophenol
CAS No.	100367-38-2
Molecular Formula	C6H6BrNO
Molecular Weight	188.02 g/mol
Synonyms	5-Bromo-3-aminophenol; 3-Amino-5-bromophenol; 5-Bromo-3-hydroxyaniline; 3-Hydroxy-5-bromoaniline; 1-Amino-3-bromo-5-hydroxybenzene; m-Amino-m-bromophenol; Phenol, 3-amino-5-bromo-
EINECS	Contact for details

Quality Control

Our 3-Amino-5-Bromophenol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR for identification, and residual solvent analysis, to ensure it meets the high standards required for synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	145 - 150 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.