Description

R(-)-8A-Methyl-3,4,8,8A-Tetrahydro-1,6(2H,7H)-Naphthalenedione is a high-purity, chiral synthetic intermediate of significant importance in advanced organic synthesis. This compound matters because its specific stereochemistry and functional groups make it a valuable building block for creating complex, optically active molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Utilized as a building block in stereoselective reactions to construct molecules with defined three-dimensional structures.
• Organic Chemistry Research: Serves as a model compound or starting material in methodological development and total synthesis projects.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Catalyst and Ligand Development: Can be used to derive novel chiral catalysts or ligands for catalytic asymmetric transformations.

Basic Information

Product Name	R(-)-8A-Methyl-3,4,8,8A-Tetrahydro-1,6(2H,7H)-Naphthalenedione
CAS No.	100348-93-4
Molecular Formula	C11H14O2
Molecular Weight	178.23 g/mol
Synonyms	(8aR)-8a-Methyl-3,4,8,8a-tetrahydro-1,6(2H,7H)-naphthalenedione; (R)-(-)-8a-Methyl-3,4,8,8a-tetrahydro-1,6-naphthalenedione; (R)-8a-Methyl-3,4,8,8a-tetrahydro-1,6(2H,7H)-naphthalenedione; (R)-8a-Methyl-3,4,8,8a-tetrahydro-1,6-naphthalenedione; (R)-8a-Methyl-3,4,8,8a-tetrahydro-1,6(2H,7H)naphthalenedione; R(-)-8a-Methyl-3,4,8,8a-tetrahydro-1,6(2H,7H)-naphthalenedione; (8aR)-8a-Methyl-3,4,8,8a-tetrahydro-1,6-naphthalenedione
EINECS	Contact for details

Quality Control

Our R(-)-8A-Methyl-3,4,8,8A-Tetrahydro-1,6(2H,7H)-Naphthalenedione is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure high chemical and chiral purity, meeting the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.