Description

5,6-Dihydro-2H-Pyran-3-Carboxylic Acid is a versatile heterocyclic building block featuring a carboxylic acid functional group on a partially saturated pyran ring. This compound matters as a key chiral intermediate in the synthesis of complex pharmaceuticals and fine chemicals, offering a valuable scaffold for medicinal chemistry. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of prostaglandins, antiviral agents, and other bioactive molecules.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Polymer Chemistry: Acts as a monomer or modifying agent for synthesizing functional polymers with tailored properties.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and medicinal chemistry research.

Basic Information

Product Name	5,6-Dihydro-2H-Pyran-3-Carboxylic Acid
CAS No.	100313-48-2
Molecular Formula	C6H8O3
Molecular Weight	128.13 g/mol
Synonyms	3,4-Dihydro-2H-pyran-5-carboxylic acid; 5,6-Dihydro-2H-pyran-3-carboxylic acid; DHP-3-COOH; 2H-Pyran-3-carboxylic acid, 5,6-dihydro-; 3-Carboxy-5,6-dihydro-2H-pyran; δ3-Dihydropyran-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5,6-Dihydro-2H-Pyran-3-Carboxylic Acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee (Specific enantiomer available)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.