Description

(3-Chloro-4-Methyl-Phenyl)-Carbamic Acid tert-Butyl Ester CAS NO 100282-49-3 is a high-purity, protected aniline derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its role as a versatile intermediate, enabling the controlled introduction of functionalized aromatic amines into complex molecular architectures. It is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting specific receptor sites.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its halogenated aromatic structure.
• Organic Synthesis Building Block: The tert-butyloxycarbonyl (Boc) protecting group allows for selective reactions, making it essential for multi-step synthetic routes in medicinal chemistry.
• Material Science Research: Employed in the creation of specialty polymers and advanced organic materials that require specific aromatic amine functionalities.
• Chemical Biology & Proteomics: Acts as a reagent for modifying peptides or proteins, or in the synthesis of molecular probes and inhibitors for biological studies.

Basic Information

Product Name	(3-Chloro-4-Methyl-Phenyl)-Carbamic Acid tert-Butyl Ester
CAS No.	100282-49-3
Molecular Formula	C12H16ClNO2
Molecular Weight	241.71 g/mol
Synonyms	tert-Butyl (3-chloro-4-methylphenyl)carbamate; N-Boc-3-chloro-4-methylaniline; Boc-3-chloro-p-toluidine; 1-(tert-Butoxycarbonylamino)-3-chloro-4-methylbenzene; (3-Chloro-4-methylphenyl)carbamic acid 1,1-dimethylethyl ester; N-(tert-Butoxycarbonyl)-3-chloro-4-methylaniline; BOC-3-Chloro-4-methylaniline; 100282-49-3
EINECS	Contact for details

Quality Control

Our (3-Chloro-4-Methyl-Phenyl)-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment ensures the material meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.