Description

27-Methyl-2,5,8,11,14,17,20,23,26-Nonaoxaoctacosane is a high-purity, synthetic polyethylene glycol (PEG) derivative, specifically a methyl-capped PEG ether. This compound is valued for its role as a versatile chemical intermediate and functional additive, offering controlled hydrophilicity and solubility. It is primarily utilized by manufacturers in the pharmaceutical, biotechnology, and specialty chemical industries for applications ranging from polymer synthesis to formulation enhancement.

Application

• Pharmaceutical Intermediate: Used in the synthesis of prodrugs, drug conjugates, and PEGylated therapeutic agents to improve solubility and pharmacokinetics.
• Polymer Chemistry: Serves as a monomer or macromonomer for creating tailored co-polymers with specific chain lengths and end-group functionality.
• Surface Modification Agent: Employed to modify the surface properties of materials, imparting hydrophilicity and reducing protein adsorption in biomedical devices.
• Formulation Additive: Acts as a solubilizer, stabilizer, or delivery enhancer in various cosmetic, personal care, and agrochemical formulations.
• Bioconjugation Linker: Provides a spacer arm in bioconjugation techniques, linking biomolecules like proteins or peptides to other entities while maintaining bioactivity.
• Research & Development: A key reagent in academic and industrial R&D for exploring new materials science, nanotechnology, and drug delivery systems.

Basic Information

Product Name	27-Methyl-2,5,8,11,14,17,20,23,26-Nonaoxaoctacosane
CAS No.	100258-40-0
Molecular Formula	C₂₉H₆₀O₉
Molecular Weight	564.78 g/mol
Synonyms	Methyl-PEG9-OH; 2,5,8,11,14,17,20,23,26-Nonaoxaoctacosan-28-ol, 27-methyl-; Poly(ethylene glycol) methyl ether (n=9); mPEG9-OH; PEG-9 methyl ether; 3,6,9,12,15,18,21,24,27-Nonaoxanonacosan-1-ol; α-Methyl-ω-hydroxy-nona(ethylene glycol); Methoxy polyethylene glycol 450
EINECS	Contact for details

Quality Control

Our 27-Methyl-2,5,8,11,14,17,20,23,26-Nonaoxaoctacosane is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and assay, NMR for structural confirmation, and KF titration for water content, to ensure it meets precise specifications. Certificates of Analysis (COA) documenting all test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Average Molecular Weight (GPC)	550 - 580 g/mol
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.