Description

4-(2-Chloroethoxy)Phenol is a versatile phenolic ether derivative with a reactive chlorinated side chain, serving as a key synthetic intermediate in advanced organic chemistry. Its molecular structure makes it valuable for constructing more complex molecules, particularly in the development of specialized polymers and active pharmaceutical ingredients (APIs). This compound is primarily sought by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty polymer industries for its utility in etherification and coupling reactions.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a phenoxy-ether linkage.
• Agrochemical Synthesis: Used in the research and production of herbicides and plant growth regulators where its phenolic and ether functionalities are incorporated.
• Polymer Chemistry: Acts as a monomer or chain modifier in the production of specialty polymers, such as polyarylates and epoxy resins, to alter thermal or chemical resistance.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of certain mesogenic compounds used in display technologies.
• Organic Synthesis Reagent: Employed in laboratory-scale organic reactions, including nucleophilic substitution and ether formation, to introduce the 2-chloroethoxyphenyl moiety.
• Dye and Pigment Intermediate: Utilized in the manufacture of certain high-performance dyes and organic pigments.

Basic Information

Product Name	4-(2-Chloroethoxy)Phenol
CAS No.	100238-55-9
Molecular Formula	C8H9ClO2
Molecular Weight	172.61 g/mol
Synonyms	1-Chloro-2-(4-hydroxyphenoxy)ethane; 4-Hydroxyphenyl 2-chloroethyl ether; 2-Chloroethyl 4-hydroxyphenyl ether; p-(2-Chloroethoxy)phenol; 4-(β-Chloroethoxy)phenol; Phenol, 4-(2-chloroethoxy)-; 2-(4-Hydroxyphenoxy)ethyl chloride
EINECS	Contact for details

Quality Control

Our 4-(2-Chloroethoxy)Phenol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing specific results for purity, appearance, and related substances is provided with every shipment. We support cGMP compliance for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	48 - 52 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.