Description

(S)-5-[(E)-Ethylidene]-5,6-Dihydro-2,3-Dimethyl-6-Oxo-2H-Pyran-2-Carboxylic Acid CAS NO 19776-81-9 is a high-purity, optically active lactone derivative that serves as a critical chiral building block and synthetic intermediate. Its unique fused pyranone structure makes it a valuable precursor for the synthesis of complex molecules in advanced research and development. This compound is primarily utilized by pharmaceutical and fine chemical industries for developing novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in oncology and antiviral therapeutic areas.
• Asymmetric Synthesis: Utilized as a building block in stereoselective organic synthesis to construct complex molecular architectures with defined chirality.
• Agrochemical Research: Serves as a precursor in the development of advanced, targeted crop protection agents and herbicides.
• Material Science: Investigated for the synthesis of specialty polymers and advanced organic materials with specific optical or electronic properties.
• Academic & R&D: Used in university and corporate research laboratories for methodological studies in synthetic organic chemistry and catalysis.
• Flavor & Fragrance Industry: Potential intermediate for the synthesis of complex, naturally-derived odorants and flavoring agents.

Basic Information

Product Name	(S)-5-[(E)-Ethylidene]-5,6-Dihydro-2,3-Dimethyl-6-Oxo-2H-Pyran-2-Carboxylic Acid
CAS No.	19776-81-9
Molecular Formula	C11H14O4
Molecular Weight	210.23 g/mol
Synonyms	(S)-5-Ethylidene-5,6-dihydro-2,3-dimethyl-6-oxo-2H-pyran-2-carboxylic acid; (5S)-5-[(1E)-Ethylidene]-5,6-dihydro-2,3-dimethyl-6-oxo-2H-pyran-2-carboxylic acid; (S)-5-(1-Ethylidene)-5,6-dihydro-2,3-dimethyl-6-oxo-2H-pyran-2-carboxylic acid; (S)-5-Ethylidenedihydro-2,3-dimethyldioxopyrancarboxylic acid; Lactone derivative CAS 19776-81-9; 2H-Pyran-2-carboxylic acid, 5,6-dihydro-5-[(1E)-ethylidene]-2,3-dimethyl-6-oxo-, (5S)-; (S)-Ethylidene dimethyl dihydro oxopyran carboxylic acid
EINECS	Contact for details

Quality Control

Our production of (S)-5-[(E)-Ethylidene]-5,6-Dihydro-2,3-Dimethyl-6-Oxo-2H-Pyran-2-Carboxylic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure high chemical and optical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to protect from moisture and potential contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.