Description

1,1',3,3,3',3'-Hexamethylindotricarbocyanine Iodide is a near-infrared (NIR) absorbing cyanine dye salt, a critical functional material for advanced photonic and biomedical applications. Its value lies in its strong absorption and fluorescence in the NIR region, where biological tissues exhibit minimal autofluorescence and light scattering. This compound is essential for researchers and manufacturers in the fields of biomedical imaging, optical data storage, laser technology, and as a sensitizer for photodynamic therapy.

Application

• Fluorescent Labeling & Probes: Used as a NIR fluorescent tag for biomolecules (antibodies, peptides, nucleic acids) in in vivo and in vitro imaging and diagnostics.
• Optical Data Storage: Acts as a light-absorbing layer in recordable optical discs (CD-R, DVD-R) and holographic storage media.
• Laser Dyes & Nonlinear Optics: Serves as a gain medium for tunable dye lasers operating in the NIR spectrum and in nonlinear optical devices.
• Photodynamic Therapy (PDT): Investigated as a photosensitizer for cancer treatment, where it generates reactive oxygen species upon NIR light irradiation.
• Solar Cells & Photovoltaics: Employed in dye-sensitized solar cells (DSSCs) and organic photovoltaics due to its light-harvesting properties.
• Sensor Development: A key component in the fabrication of chemical and biological sensors that utilize NIR fluorescence or absorption changes.

Basic Information

Product Name	1,1',3,3,3',3'-Hexamethylindotricarbocyanine Iodide
CAS No.	19764-96-6
Molecular Formula	C45H51I2N2
Molecular Weight	881.72 g/mol
Synonyms	HITCI Iodide; Hexamethylindotricarbocyanine Iodide; 1,1',3,3,3',3'-Hexamethyl-4,4',5,5'-dibenzoindotricarbocyanine Iodide; IR-125; NIR Dye 125; 1,1',3,3,3',3'-Hexamethylindodicarbocyanine Iodide (common misnomer); HITC Iodide; Astrazon IR 125
EINECS	Contact for details

Quality Control

Our production of 1,1',3,3,3',3'-Hexamethylindotricarbocyanine Iodide adheres to stringent quality protocols to ensure batch-to-batch consistency and performance reliability for research and industrial applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, UV-Vis-NIR spectroscopy for absorption profile verification, and elemental analysis. A detailed Certificate of Analysis (COA) documenting identity, purity, and key spectral properties is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive; prolonged exposure to light may cause degradation. For long-term stability, consider storage under inert atmosphere (argon or nitrogen) and desiccation.

Specification

Item	Specification
Appearance	Dark green to blue-black crystalline powder
Identification (UV-Vis)	Characteristic absorption maxima in Methanol
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 95.0% (Area Percent)
λmax (Methanol)	~785 nm ± 5 nm
Extinction Coefficient (ε)	≥ 200,000 L·mol⁻¹·cm⁻¹
Loss on Drying	≤ 2.0 %
Residue on Ignition	≤ 0.5 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.