Description

1,2-o-Isopropylidene-5-Keto-α-D-Glucose is a key chiral intermediate and protected sugar derivative widely used in organic synthesis. This compound is valued for its role as a versatile building block in the production of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is essential for chemists and process developers in the life sciences, agrochemical, and specialty chemical industries seeking to introduce specific stereochemistry and functional groups into their target compounds.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of nucleoside analogs, antiviral agents, and other active pharmaceutical ingredients (APIs).
• Carbohydrate Chemistry Research: Serves as a protected starting material for the study and synthesis of complex sugars, glycoconjugates, and glycomimetics.
• Fine Chemical Synthesis: Used as a chiral synthon for constructing natural products, flavors, fragrances, and other high-value specialty chemicals.
• Agrochemical Development: Employed in the research and production of advanced crop protection agents and plant growth regulators.
• Biochemical Tool: Acts as a substrate or inhibitor in enzymatic studies and biochemical assays related to carbohydrate metabolism.
• Material Science: Potential monomer or modifier in the development of biodegradable polymers and advanced functional materials.

Basic Information

Product Name	1,2-o-Isopropylidene-5-Keto-α-D-Glucose
CAS No.	19684-32-3
Molecular Formula	C9H14O6
Molecular Weight	218.20 g/mol
Synonyms	5-Keto-1,2-O-isopropylidene-α-D-glucofuranose; 1,2-O-Isopropylidene-α-D-glucofuranurono-6,3-lactone; 1,2:5,6-Di-O-isopropylidene-α-D-glucofuranose-3-ulose; Diacetone glucose ketone; 3-Keto-1,2:5,6-di-O-isopropylidene-α-D-glucofuranose; α-D-Glucofuranose, 1,2-O-(1-methylethylidene)-, 5-oxo-
EINECS	243-200-8

Quality Control

Our 1,2-o-Isopropylidene-5-Keto-α-D-Glucose is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Specific Rotation [α]20/D	-40° to -45° (c=1 in H2O)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.