Description

(3R)-3,4,4A,5,6,7,8,8Aβ-Octahydro-4Aβ,5β-Dimethyl-3β-(1-Methylethyl)Naphthalen-2(1H)-One is a high-purity, stereochemically defined decalin derivative that serves as a critical chiral building block and intermediate in advanced organic synthesis. Its rigid, fused-ring structure and defined stereocenters make it invaluable for constructing complex molecular architectures with precise three-dimensional control. This compound is primarily sought by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and fragrance sectors for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel therapeutic agents, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where its stereochemistry can influence biological activity.
• Fragrance & Flavor Chemistry: Serves as a starting material for synthesizing complex, naturally-inspired odorants and flavor compounds with woody, amber, or musk characteristics.
• Material Science Research: Employed as a monomer or modifying agent in the development of specialty polymers with tailored thermal or mechanical properties.
• Catalyst & Ligand Development: Acts as a backbone for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Academic & Process Chemistry: A valuable reference standard and tool for methodological studies in total synthesis and stereoselective transformations.

Basic Information

Product Name	(3R)-3,4,4A,5,6,7,8,8Aβ-Octahydro-4Aβ,5β-Dimethyl-3β-(1-Methylethyl)Naphthalen-2(1H)-One
CAS No.	19593-08-9
Molecular Formula	C15H24O
Molecular Weight	220.35 g/mol
Synonyms	(3R)-3-Isopropyl-4a,5-dimethyl-4,4a,5,6,7,8-hexahydro-2(3H)-naphthalenone; (3R)-3-Isopropyl-4a,5-dimethyl-4,4a,5,6,7,8-hexahydronaphthalen-2(3H)-one; (3R)-3-(1-Methylethyl)-4a,5-dimethyl-3,4,4a,5,6,7,8,8a-octahydro-2(1H)-naphthalenone; (3R)-3-Isopropyl-4a,5-dimethyl-3,4,4a,5,6,7,8,8a-octahydro-2(1H)-naphthalenone; (+)-3-Isopropyl-4a,5-dimethyl-4,4a,5,6,7,8-hexahydro-2(3H)-naphthalenone; (R)-3-Isopropyl-4a,5-dimethyl-4,4a,5,6,7,8-hexahydro-2(3H)-naphthalenone; Decalin derivative intermediate
EINECS	Contact for details

Quality Control

Our (3R)-3,4,4A,5,6,7,8,8Aβ-Octahydro-4Aβ,5β-Dimethyl-3β-(1-Methylethyl)Naphthalen-2(1H)-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure high chemical and stereochemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.