Description

5-Chlorovanillin is a halogenated derivative of vanillin, a key synthetic intermediate and building block in organic chemistry. This compound matters for its role in introducing both the vanillin scaffold and a reactive chlorine atom into more complex molecular structures, enabling the synthesis of novel fine chemicals and active pharmaceutical ingredients. Industries that require this high-purity intermediate include pharmaceutical R&D, agrochemical manufacturing, and specialty fragrance synthesis.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), particularly those targeting specific receptor sites.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the chlorovanillin structure can impart specific biological activity.
• Flavor & Fragrance Ingredient: Acts as a building block for creating unique, modified vanillin derivatives with altered olfactory or taste properties for specialty applications.
• Organic Synthesis Building Block: Employed in academic and industrial research laboratories for constructing complex heterocyclic compounds and fine chemicals.
• Chemical Research: Utilized as a standard or reagent in methodological studies, including catalysis research and the development of new synthetic pathways.
• Material Science Precursor: Can be used in the development of specialty polymers or functional materials that incorporate aromatic aldehyde functionalities.

Basic Information

Product Name	5-Chlorovanillin
CAS No.	19463-48-0
Molecular Formula	C8H7ClO3
Molecular Weight	186.59 g/mol
Synonyms	5-Chlorovanillin; 3-Methoxy-4-hydroxy-5-chlorobenzaldehyde; 4-Hydroxy-3-methoxy-5-chlorobenzaldehyde; 5-Chloro-3-methoxy-4-hydroxybenzaldehyde; Vanillin, 5-chloro-; 5-Chloroprotocatechuic aldehyde methyl ether; 19463-48-0; NSC 403697
EINECS	243-104-8

Quality Control

Our 5-Chlorovanillin is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR for identification, and loss on drying, to ensure it meets exacting standards for use in sensitive applications like pharmaceutical synthesis. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity to be easily oxidized, prolonged exposure to light, air, or elevated temperatures should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	163 - 167 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.