Description

(+)-1,5,5-Trimethyl-2-Thiabicyclo[2.2.2]Octane CAS NO 19296-90-3 is a high-purity, chiral organosulfur compound characterized by its unique bicyclic structure. This compound is valued for its role as a versatile chiral building block and ligand in advanced synthetic chemistry and catalysis. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of complex, optically active molecules.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drugs.
• Catalyst Ligand: Utilized as a chiral ligand in asymmetric synthesis and transition metal catalysis to induce high enantioselectivity in critical bond-forming reactions.
• Agrochemical Synthesis: Employed in the development of new, optically pure pesticides and herbicides where specific stereochemistry is crucial for biological activity.
• Flavor & Fragrance Chemistry: Acts as a precursor for the synthesis of complex, sulfur-containing aroma compounds with specific stereochemical profiles.
• Material Science Research: Investigated as a monomer or additive for creating novel polymers with specific optical or electronic properties.
• Academic & Industrial R&D: Used in methodological studies and process development for asymmetric synthesis across chemical disciplines.

Basic Information

Product Name	(+)-1,5,5-Trimethyl-2-thiabicyclo[2.2.2]octane
CAS No.	19296-90-3
Molecular Formula	C9H16S
Molecular Weight	156.29 g/mol
Synonyms	(+)-1,5,5-Trimethyl-2-thia-2-bicyclo[2.2.2]octane; (+)-Thioisoborneol; (1R,4R)-1,7,7-Trimethyl-2-thiabicyclo[2.2.2]octane; (1R,4R)-2-Thiabicyclo[2.2.2]octane, 1,5,5-trimethyl-; (+)-1,5,5-Trimethyl-2-thiabicyclo[2.2.2]octane; Thiocamphor derivative
EINECS	Contact for details

Quality Control

Our (+)-1,5,5-Trimethyl-2-Thiabicyclo[2.2.2]Octane is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC and GC, to ensure compliance with exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider maintaining under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Specific Rotation [α]	Contact for details
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.