Description

Bromoethyltriflate CAS NO 19263-21-9 is a highly reactive alkylating agent and trifluoromethanesulfonate ester, valued for its role as a versatile synthon in advanced organic synthesis. Its primary importance lies in its ability to efficiently introduce the bromoethyl group under mild conditions, making it a critical reagent for constructing complex molecular architectures. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for nucleoside modification and the synthesis of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel nucleoside analogs and antiviral/anticancer drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides requiring specific alkylation steps.
• Material Science: Employed in the surface functionalization of polymers and the creation of specialized monomers.
• Chemical Biology: Acts as a reagent for labeling biomolecules or modifying peptides and nucleotides in probe development.
• Organic Synthesis: A pivotal reagent for C-alkylation reactions, cyclization processes, and the preparation of complex ethers and sulfonates.
• Process Chemistry: Utilized in scale-up and optimization for the manufacturing of fine chemicals and advanced intermediates.

Basic Information

Item	Details
Product Name	Bromoethyltriflate
CAS No.	19263-21-9
Molecular Formula	C3H4BrF3O3S
Molecular Weight	257.02 g/mol
Synonyms	2-Bromoethyl trifluoromethanesulfonate; 2-Bromoethyl triflate; Trifluoromethanesulfonic acid 2-bromoethyl ester; Bromoethyl trifluoromethanesulfonate; 1-Bromo-2-[(trifluoromethyl)sulfonyloxy]ethane; Ethanol, 2-bromo-, 1-trifluoromethanesulfonate; NSC 401119
EINECS	Contact for details

Quality Control

Every batch of Bromoethyltriflate is produced and analyzed under strict quality management protocols to ensure consistency and high purity for demanding synthetic applications. Our products undergo rigorous quality testing, including chromatographic purity analysis and identity confirmation, to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed chromatograms and spectroscopic data are available upon request to support your regulatory and R&D documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases and nucleophiles.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.