Description

1,2:5,6-Di-o-Isopropylidene-3-o-Tosyl-α-D-Gulofuranose is a high-purity, protected carbohydrate derivative that serves as a critical chiral building block and synthetic intermediate. Its value lies in providing a versatile, functionalized scaffold for the stereoselective construction of complex molecules, particularly in pharmaceutical research and development. This compound is essential for chemists and manufacturers in the life sciences sector who require reliable access to high-quality intermediates for synthesizing nucleosides, antibiotics, and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of nucleoside analogues and antiviral/antitumor agents.
• Glycochemistry Research: Used as a protected sugar donor or acceptor for constructing complex oligosaccharides and glycoconjugates.
• Chemical Biology Probes: Employed in the development of labeled sugars and metabolic probes for studying biological pathways.
• Asymmetric Synthesis: Serves as a chiral auxiliary or starting material for the preparation of enantiomerically pure natural products and fine chemicals.
• Process Development: Utilized in scaling up routes to carbohydrate-based active pharmaceutical ingredients (APIs).
• Academic & Industrial R&D: A valuable reagent for methodology development in organic synthesis and medicinal chemistry programs.

Basic Information

Item	Details
Product Name	1,2:5,6-Di-o-Isopropylidene-3-o-Tosyl-α-D-Gulofuranose
CAS No.	19131-06-7
Molecular Formula	C19H26O8S
Molecular Weight	414.47 g/mol
Synonyms	1,2:5,6-Di-O-isopropylidene-3-O-tosyl-α-D-glucofuranose; 3-O-Tosyl-1,2:5,6-di-O-isopropylidene-α-D-glucofuranose; 1,2:5,6-Di-O-isopropylidene-α-D-glucofuranose 3-tosylate; Diacetone glucose 3-tosylate; DAG 3-tosylate; 3-O-p-Toluenesulfonyl-1,2:5,6-di-O-isopropylidene-α-D-glucofuranose; α-D-Gulofuranose, 1,2:5,6-di-O-(1-methylethylidene)-3-O-(4-methylphenyl)sulfonyl-
EINECS	Contact for details

Quality Control

Our 1,2:5,6-Di-o-Isopropylidene-3-o-Tosyl-α-D-Gulofuranose is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.