Description

7-Chloro-2H-Chromen-2-One is a versatile chlorinated coumarin derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique halogenated coumarin scaffold makes it a valuable building block for the development of novel compounds with specific biological and photophysical properties. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to develop new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting anticoagulant, anti-inflammatory, or antimicrobial pathways.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the coumarin core can be functionalized to create bioactive molecules.
• Fluorescent Probe & Dye Synthesis: Serves as a starting material for creating advanced fluorescent tags, sensors, and optical brightening agents due to the inherent photostability of the coumarin structure.
• Organic Electronic Materials: Investigated as a building block for organic light-emitting diodes (OLEDs) and other electronic materials where its electron-transport properties are beneficial.
• Chemical Biology & Proteomics: Utilized in the design of activity-based probes and molecular tags for studying enzyme function and protein interactions.
• Academic & Contract Research: A fundamental reagent for synthetic organic chemistry research in universities and contract research organizations (CROs).

Basic Information

Product Name	7-Chloro-2H-Chromen-2-One
CAS No.	19063-54-8
Molecular Formula	C9H5ClO2
Molecular Weight	180.59 g/mol
Synonyms	7-Chlorocoumarin; 7-Chloro-2H-1-benzopyran-2-one; 7-Chloro-1-benzopyran-2-one; 7-Chloro-2-oxo-2H-chromene; 7-Chloro-2H-chromen-2-one; 7-Chloro-2-chromenone; 7-Chloro-coumarin
EINECS	242-800-5

Quality Control

Our 7-Chloro-2H-Chromen-2-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed results from HPLC, GC, NMR, and mass spectrometry. Our quality commitment ensures the material meets the stringent requirements for research and development as well as scale-up synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	148°C - 152°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.