Description

4-Methoxyphenyl Mesylate, also known as 4-[(Methylsulphonyl)Oxy]Anisole, is a versatile aryl mesylate ester and a key chemical intermediate in advanced organic synthesis. Its value lies in its role as a protected phenol derivative and an excellent leaving group, enabling precise and efficient construction of complex molecular architectures. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to introduce the 4-methoxyphenyl moiety or to serve as a precursor in cross-coupling reactions and nucleophilic substitutions.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing substituted aromatic ethers.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and insecticides that require specific phenoxy-based structures.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in homogeneous catalysis and material science.
• Polymer Chemistry: Employed in the creation of monomers and functional polymers with tailored thermal and chemical properties.
• Organic Synthesis Reagent: Functions as an electrophile in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions due to the mesylate leaving group.
• Chemical Research & Development: A valuable tool in academic and industrial R&D for exploring new reaction pathways and synthesizing novel organic compounds.

Basic Information

Product Name	4-Methoxyphenyl Mesylate
CAS No.	19013-30-0
Molecular Formula	C8H10O4S
Molecular Weight	202.23 g/mol
Synonyms	4-[(Methylsulphonyl)Oxy]Anisole; p-Methoxyphenyl Methanesulfonate; Anisole, 4-[(methylsulfonyl)oxy]-; 4-Methoxyphenyl Methanesulfonate; 1-Methoxy-4-(methylsulfonyloxy)benzene; 4-Methoxybenzenyl Mesylate; 4-MOPM; 19013-30-0
EINECS	Contact for details

Quality Control

Our 4-Methoxyphenyl Mesylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.