Description

3α-Trimethylsilyloxy-5α-Cholestane is a high-purity, organosilicon-modified steroidal compound used as a critical intermediate and reference standard in advanced chemical synthesis. Its value lies in providing a protected hydroxyl group on the cholestane backbone, enabling precise and selective reactions in complex molecular construction. This product is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors, particularly those developing novel steroid-based therapeutics, high-value agrochemicals, and sophisticated organic materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel steroid-based drugs, hormone analogs, and other bioactive molecules.
• Reference Standard: Used in analytical chemistry for method development, calibration, and quality control in steroid analysis via HPLC, GC-MS, or NMR.
• Chemical Research: Serves as a versatile starting material or protected intermediate in academic and industrial organic chemistry research.
• Fine Chemical Synthesis: Employed in the production of specialized steroidal compounds for agrochemicals, materials science, and diagnostics.
• Metabolic Studies: Can be utilized as a derivatization agent or tracer in biochemical and metabolic pathway research.

Basic Information

Product Name	3α-Trimethylsilyloxy-5α-Cholestane
CAS No.	18880-50-7
Molecular Formula	C₃₀H₅₄OSi
Molecular Weight	458.84 g/mol
Synonyms	Cholestane, 3-(trimethylsilyl)oxy-, (3α,5α)-; (3α,5α)-3-(Trimethylsilyloxy)cholestane; 5α-Cholestan-3α-ol trimethylsilyl ether; 3α-Trimethylsiloxy-5α-cholestane; 3-TMS-5α-cholestane; TMS-Cholestane Derivative; Steroid TMS Ether
EINECS	Contact for details

Quality Control

Our 3α-Trimethylsilyloxy-5α-Cholestane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatographic purity assays and structural confirmation. A Certificate of Analysis (COA) detailing specific results for identity, purity, and impurities is provided with every shipment, supporting compliance with research and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.