Description

Ac-Gln-NH2 is a protected glutamine derivative, specifically N-Acetyl-L-glutamine amide, widely used as a key building block in peptide synthesis and pharmaceutical research. This high-purity intermediate is critical for ensuring the integrity and bioactivity of complex peptide sequences, offering researchers and manufacturers precise control over molecular structure. It serves the needs of the pharmaceutical, biotechnology, and life science industries for developing novel therapeutic agents and biochemical tools.

Application

• Peptide Synthesis: Serves as a crucial protected amino acid building block (Fmoc or Boc chemistry) for solid-phase and solution-phase peptide synthesis.
• Pharmaceutical Intermediates: Used in the research and development of potential therapeutic peptides and protein-based drugs.
• Biochemical Research: Employed as a substrate or standard in enzymatic studies and metabolic pathway investigations.
• Protecting Group Strategy: The acetyl (Ac) and amide (NH2) groups provide orthogonal protection for the glutamine side chain during multi-step organic syntheses.
• Combinatorial Chemistry: A valuable component in libraries for drug discovery and high-throughput screening.

Basic Information

Product Name	Ac-Gln-NH2
CAS No.	18839-88-8
Molecular Formula	C7H13N3O3
Molecular Weight	187.20 g/mol
Synonyms	N-Acetyl-L-glutamine amide; N2-Acetyl-L-glutaminamide; Ac-L-Gln-NH2; (S)-2-Acetamidopentanediamide; L-Glutamine, N-acetyl-, amide; N-Acetylglutamine amide; Nα-Acetyl-L-glutamine amide; Ac-Gln-NH2
EINECS	Contact for details

Quality Control

Our Ac-Gln-NH2 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive research and production applications. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed HPLC purity, chiral purity, and impurity profiles. The product meets stringent specifications suitable for pharmaceutical research and cGMP-guided applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent absorption of moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-Isomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.