Description

1-Acetyl-4-Hydroxy-2,5-Dihydro-1H-Pyrrole-3-Carbonitrile is a versatile heterocyclic building block featuring a pyrrolidine core functionalized with acetyl, hydroxyl, and nitrile groups. This unique molecular architecture makes it a critical intermediate for synthesizing complex pharmaceuticals and advanced agrochemicals. It is essential for research chemists and process development scientists in the fine chemical, pharmaceutical, and agrochemical industries seeking to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in classes like kinase inhibitors, antiviral agents, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of advanced herbicides, fungicides, and plant growth regulators, leveraging its reactive nitrile and hydroxyl functionalities.
• Fine Chemical Building Block: Used in organic synthesis to construct complex nitrogen-containing heterocycles for material science and specialty chemical applications.
• Research & Development (R&D): A valuable compound for academic and industrial R&D focused on medicinal chemistry and novel synthetic methodology development.
• Chemical Biology Probe Development: Utilized in the synthesis of molecular probes for studying biological pathways and enzyme functions.

Basic Information

Product Name	1-Acetyl-4-Hydroxy-2,5-Dihydro-1H-Pyrrole-3-Carbonitrile
CAS No.	18721-38-5
Molecular Formula	C7H8N2O2
Molecular Weight	152.15 g/mol
Synonyms	4-Hydroxy-1-acetyl-2,5-dihydro-1H-pyrrole-3-carbonitrile; 1-Acetyl-4-hydroxy-2,5-dihydro-3-cyanopyrrole; 3-Cyano-4-hydroxy-1-acetyl-2,5-dihydropyrrole; 4-Hydroxy-1-acetyl-2,5-dihydro-3-pyrrolecarbonitrile; 1H-Pyrrole-3-carbonitrile, 1-acetyl-4-hydroxy-2,5-dihydro-; 1-Acetyl-4-hydroxy-2,5-dihydro-pyrrole-3-carbonitrile; 18721-38-5
EINECS	Contact for details

Quality Control

Our 1-Acetyl-4-Hydroxy-2,5-Dihydro-1H-Pyrrole-3-Carbonitrile is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.