Description

1-Amino-Decahydro-1-Naphthalenecarboxylic Acid is a specialized, high-purity bicyclic amino acid derivative with a rigid decalin backbone. This compound matters as a versatile and structurally constrained chiral building block, enabling the synthesis of complex molecules with precise stereochemistry. It is primarily needed by research institutions and pharmaceutical companies engaged in developing novel active pharmaceutical ingredients (APIs), peptide mimetics, and advanced chemical intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and metabolic disease targets.
• Peptidomimetics & Constrained Peptide Design: Used to introduce conformational rigidity into peptide chains, enhancing metabolic stability and binding affinity for drug discovery programs.
• Asymmetric Synthesis: Serves as a chiral auxiliary or starting material in stereoselective catalytic reactions to construct complex molecular architectures.
• Ligand & Catalyst Development: Employed in the synthesis of novel chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Academic & Industrial Research: A valuable tool for methodological studies in organic chemistry and medicinal chemistry for exploring new synthetic pathways.
• Fine Chemical Production: Used in the custom synthesis of high-value, low-volume specialty chemicals for advanced material science applications.

Basic Information

Product Name	1-Amino-Decahydro-1-Naphthalenecarboxylic Acid
CAS No.	18672-75-8
Molecular Formula	C11H19NO2
Molecular Weight	197.27 g/mol
Synonyms	1-Aminodecahydro-2-naphthoic Acid; 1-Amino-1,2,3,4,4a,5,6,7,8,8a-decahydro-2-naphthalenecarboxylic Acid; 1-Amino-decahydronaphthalene-1-carboxylic Acid; (1R,2R,4aS,8aS)-1-Amino-1,2,3,4,4a,5,6,7,8,8a-decahydro-2-naphthoic Acid; (1S,2S,4aR,8aR)-1-Amino-1,2,3,4,4a,5,6,7,8,8a-decahydro-2-naphthoic Acid; cis-1-Amino-2-decalincarboxylic Acid; 1-Amino-2-carboxydecahydronaphthalene; Decahydro-1-amino-2-naphthoic Acid
EINECS	Contact for details

Quality Control

Our 1-Amino-Decahydro-1-Naphthalenecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical research and fine chemical synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), chiral purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.