Description

3-Ethynyl-2-Hydroxy-Phenol is a specialized phenolic compound featuring both an ethynyl and a hydroxyl group on the aromatic ring, making it a versatile intermediate for advanced organic synthesis. This unique structure is critical for constructing complex molecular architectures, particularly in pharmaceutical research and materials science. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications requiring precise functional group manipulation.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting neurological and oncological pathways.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Material Science Precursor: Acts as a monomer or cross-linking agent in the development of advanced polymers, resins, and conductive materials.
• Ligand Synthesis: Employed in the creation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Research: A valuable tool in academic and industrial laboratories for methodology development and exploring new chemical spaces.
• Dye & Pigment Intermediate: Utilized in the synthesis of complex organic dyes and functional pigments.

Basic Information

Product Name	3-Ethynyl-2-Hydroxy-Phenol
CAS No.	18649-64-4
Molecular Formula	C8H6O2
Molecular Weight	134.13 g/mol
Synonyms	2-Hydroxy-3-ethynylphenol; 3-Ethynylpyrocatechol; 3-Ethynylbenzene-1,2-diol; 3-Ethynylcatechol; 1,2-Dihydroxy-3-ethynylbenzene; 3-Ethynyl-1,2-benzenediol; 3-Ethynyl-2-hydroxyphenol (common name)
EINECS	Contact for details

Quality Control

Our 3-Ethynyl-2-Hydroxy-Phenol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound may be light-sensitive and should be handled under an inert atmosphere for long-term storage to prevent potential oxidation.

Specification

Item	Specification
Appearance	Off-white to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.