Description

3-Amino-n-Cbz-Dl-Alanine is a protected amino acid derivative featuring both an amino group and a carboxybenzyl (Cbz) protecting group. This compound is a crucial chiral building block and intermediate in the synthesis of complex peptides and peptidomimetics, offering versatility for selective deprotection strategies. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents and biochemical tools.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis as a protected amino acid building block to control regiochemistry.
• Biochemical Research: Acts as a precursor or standard in metabolic studies and enzyme inhibition research.
• Protecting Group Chemistry: The Cbz group allows for orthogonal protection strategies, enabling complex multi-step synthetic sequences.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands for asymmetric catalysis or metal complexes.

Basic Information

Product Name	3-Amino-n-Cbz-Dl-Alanine
CAS No.	18635-43-3
Molecular Formula	C11H14N2O4
Molecular Weight	238.24 g/mol
Synonyms	Nα-Carbobenzyloxy-3,3-diaminopropionic Acid; N-Cbz-3,3-diaminopropanoic Acid; 3-Amino-N-(benzyloxycarbonyl)-DL-alanine; (2R/S)-2-[(Benzyloxy)carbonylamino]-3-aminopropanoic Acid; Cbz-DL-Dap-OH; Z-DL-Dap-OH; N-Carbobenzyloxy-β,β-diaminopropionic Acid; DL-3-Amino-N-carbobenzyloxyalanine
EINECS	Contact for details

Quality Control

Our 3-Amino-n-Cbz-Dl-Alanine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via spectroscopic methods. We provide full traceability and a Certificate of Analysis (COA) with every shipment, ensuring compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Purity (Chiral HPLC)	DL-mixture (Racemic)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.