Description

α-[(Pyrido[3,4-D]Pyridazin-5-Yl)Thio]Acetophenone is a specialized heterocyclic organic compound featuring a pyridopyridazine core linked to an acetophenone moiety via a thioether bridge. This unique molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block for research and development. It is primarily sought after by pharmaceutical R&D and fine chemical synthesis teams for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing specific enzyme inhibitory activity.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Material Science Precursor: Serves as a starting material for synthesizing complex organic ligands used in catalysis or functional polymers.
• Academic & Contract Research: Employed in university and CRO laboratories for medicinal chemistry programs and structure-activity relationship (SAR) studies.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	α-[(Pyrido[3,4-D]Pyridazin-5-Yl)Thio]Acetophenone
CAS No.	18599-27-4
Molecular Formula	C15H11N3OS
Molecular Weight	281.33 g/mol
Synonyms	2-[(Pyrido[3,4-d]pyridazin-5-yl)sulfanyl]-1-phenylethanone; 1-Phenylethanone, 2-[(pyrido[3,4-d]pyridazin-5-yl)thio]-; α-(Pyrido[3,4-d]pyridazin-5-ylthio)acetophenone; 5-[(2-Oxo-2-phenylethyl)thio]pyrido[3,4-d]pyridazine; 18599-27-4; Pyrido[3,4-d]pyridazin-5-ylthioacetophenone
EINECS	Contact for details

Quality Control

Our α-[(Pyrido[3,4-D]Pyridazin-5-Yl)Thio]Acetophenone is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications and test results are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Standard Grade)
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.