Description

m-Carborane-1-Carboxylic Acid CAS NO 18581-81-2 is a high-purity, functionalized carborane derivative serving as a critical building block in advanced materials science and medicinal chemistry. Its unique icosahedral carborane cage structure, modified with a carboxylic acid group, provides exceptional thermal stability, chemical inertness, and versatile reactivity for precise molecular design. This compound is essential for researchers and manufacturers developing boron neutron capture therapy (BNCT) agents, high-performance polymers, thermally stable ligands for catalysis, and novel organometallic complexes.

Application

• Boron Neutron Capture Therapy (BNCT): A key precursor for synthesizing tumor-targeting boron delivery agents due to its high boron content and modifiable carboxylic acid functionality.
• Advanced Polymer Synthesis: Used as a monomer or cross-linking agent to create polycarboranesiloxanes and other polymers with exceptional thermal and oxidative stability for aerospace and electronics.
• Organometallic Chemistry & Catalysis: Serves as a robust, sterically demanding ligand precursor for transition metal complexes, enhancing catalyst stability and performance.
• Materials Science: Incorporated into novel liquid crystals, dendrimers, and metal-organic frameworks (MOFs) to impart unique electronic and structural properties.
• Pharmaceutical Intermediate: Employed in the research and development of novel pharmacophores where the carborane cage is used as a hydrophobic, metabolically stable phenyl bioisostere.
• Radiation Shielding Materials: A component in formulations for creating lightweight, efficient neutron shielding materials due to boron's high neutron capture cross-section.

Basic Information

Product Name	m-Carborane-1-Carboxylic Acid
CAS No.	18581-81-2
Molecular Formula	C3H12B10O2
Molecular Weight	195.82 g/mol
Synonyms	1-Carboxy-m-carborane; 1-Carboxy-1,7-dicarbadodecaborane(12); m-Carborane-1-carboxylic acid; 1,7-Dicarbadodecaborane(12)-1-carboxylic acid; 1-Carboxylic acid-m-carborane; 1-H-Carborane-1-carboxylic acid (7-isomer); 1,7-Carboranedicarboxylic acid (monoacid); BRN 4167578
EINECS	Contact for details

Quality Control

Our m-Carborane-1-Carboxylic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized using advanced analytical techniques including NMR (1H, 11B, 13C), HPLC, and FT-IR. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
1H NMR	Conforms to structure
11B NMR	Conforms to structure
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Solubility	Soluble in polar organic solvents (e.g., DMSO, DMF, THF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.