Description

[(3-Chlorophenyl)Thio]Acetonitrile is a versatile sulfur-containing aromatic nitrile building block, essential for advanced organic synthesis. Its core value lies in enabling the efficient construction of complex heterocyclic and pharmaceutical intermediates. This high-purity compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active molecules and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of thioether-containing drug candidates, including potential kinase inhibitors and antimicrobial agents.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides that leverage the bioactivity of the chlorophenylthio moiety.
• Ligand and Catalyst Development: Used to prepare specialized ligands for transition metal catalysis, facilitating challenging cross-coupling reactions.
• Material Science Research: Serves as a monomer or functionalization agent in the development of advanced polymers with specific electronic or adhesive properties.
• Chemical Biology Probes: Employed in the design and synthesis of activity-based probes for studying enzyme function and metabolic pathways.

Basic Information

Product Name	[(3-Chlorophenyl)Thio]Acetonitrile
CAS No.	18527-22-5
Molecular Formula	C8H6ClNS
Molecular Weight	183.66 g/mol
Synonyms	(3-Chlorophenylthio)acetonitrile; 2-[(3-Chlorophenyl)sulfanyl]acetonitrile; 3-Chlorophenyl thiocyanatomethane; 3-Chlorobenzenecarbothioic acid, cyano-methyl ester; α-[(3-Chlorophenyl)thio]acetonitrile; NSC 163081; (3-Chlorophenylsulfanyl)acetonitrile
EINECS	Contact for details

Quality Control

Our [(3-Chlorophenyl)Thio]Acetonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support compliance with relevant regulatory frameworks for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.