Description

(4-Fluorophenylthio)Acetonitrile is a versatile sulfur-containing nitrile building block, essential for constructing complex molecular architectures in advanced organic synthesis. Its core value lies in the strategic combination of a fluorinated aromatic ring and a reactive nitrile group, enabling precise modifications to enhance the properties of target compounds. This intermediate is particularly valuable for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require high-purity, reliable components for drug discovery and specialty chemical production.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in the synthesis of compounds with potential biological activity.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging the fluorine atom for improved efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and catalysts used in asymmetric synthesis and transition metal catalysis.
• Material Science Research: Employed in the synthesis of advanced polymers, liquid crystals, and organic electronic materials where the fluorine and sulfur groups impart specific physical properties.
• Chemical Biology Probes: Useful in the design and synthesis of molecular probes and tags for studying biological systems and mechanisms.

Basic Information

Product Name	(4-Fluorophenylthio)Acetonitrile
CAS No.	18527-21-4
Molecular Formula	C8H6FNS
Molecular Weight	167.20 g/mol
Synonyms	2-[(4-Fluorophenyl)sulfanyl]acetonitrile; (p-Fluorophenylthio)acetonitrile; 4-Fluorophenyl thiocyanatomethane; 4-Fluorobenzenethioacetonitrile; Acetonitrile, (4-fluorophenylthio)-; 4-Fluorophenylmercaptoacetonitrile; 4-Fluorothiophenol cyanomethyl ether
EINECS	Contact for details

Quality Control

Every batch of (4-Fluorophenylthio)Acetonitrile is manufactured and tested under a strict quality management system to ensure consistency and reliability for your critical applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques. Our commitment to quality supports compliance with ISO standards and meets the rigorous demands of research and cGMP manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber packaging during storage.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.