Description

2-[(4-Bromophenyl)Thio]-2-Methyl-Propanoic Acid is a high-purity, sulfur-containing organic building block of significant interest in advanced chemical synthesis. Its unique structure, featuring a bromophenyl thioether and a tertiary carboxylic acid, makes it a versatile intermediate for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting specific enzyme inhibition or receptor modulation.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators, leveraging its bio-active scaffold.
• Ligand and Catalyst Development: Acts as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Precursor: Employed in the research of organic electronic materials, such as semiconductors or charge-transport layers, due to its conjugated aromatic-thioether system.
• Chemical Biology Probe Synthesis: Utilized to build molecular probes for studying biological pathways and protein functions.
• Custom Synthesis & Contract Manufacturing: A critical building block for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	2-[(4-Bromophenyl)Thio]-2-Methyl-Propanoic Acid
CAS No.	18527-16-7
Molecular Formula	C10H11BrO2S
Molecular Weight	275.16 g/mol
Synonyms	2-[(4-Bromophenyl)sulfanyl]-2-methylpropanoic acid; 2-Methyl-2-[(4-bromophenyl)thio]propanoic acid; α-[(p-Bromophenyl)thio]isobutyric acid; p-Bromophenyl 2-methyl-2-carboxyethyl sulfide; 4-Bromobenzenethiol, 2-methyl-2-carboxyethyl derivative; 2-(4-Bromophenylthio)-2-methylpropionic acid; 18527-16-7; NSC 403079
EINECS	Contact for details

Quality Control

Our 2-[(4-Bromophenyl)Thio]-2-Methyl-Propanoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.