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Formononetin-7-o-Glucuronide CAS NO 18524-03-3


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CAS No.:18524-03-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Formononetin-7-o-Glucuronide is a specific glucuronide conjugate of the isoflavone formononetin, a compound of significant interest in phytochemical and pharmacological research. This metabolite is crucial for studying the bioavailability, pharmacokinetics, and biological activity of formononetin in various systems. It serves as a high-purity reference standard and key intermediate for researchers and manufacturers in the nutraceutical, pharmaceutical, and life science sectors who require precise compounds for analytical and developmental work.

Application

  • Pharmaceutical Reference Standard: Used as a certified standard for the quantitative and qualitative analysis (HPLC, LC-MS) of formononetin and its metabolites in drug development and quality control.
  • Nutraceutical & Dietary Supplement Research: Essential for studying the metabolic pathways, bioavailability, and efficacy of soy and red clover-derived isoflavone supplements.
  • Biochemical Research: Employed in in vitro and in vivo studies to investigate the anti-inflammatory, antioxidant, and potential hormonal activities of isoflavone metabolites.
  • Metabolite Identification & Biomarker Development: A critical tool for identifying formononetin metabolites in biological fluids (plasma, urine) for clinical and toxicological studies.
  • Cosmeceutical Ingredient Development: Investigated for potential applications in skincare formulations targeting aging and inflammation due to its bioactive properties.

Basic Information

Product Name Formononetin-7-o-Glucuronide
CAS No. 18524-03-3
Molecular Formula C22H20O10
Molecular Weight 444.39 g/mol
Synonyms Formononetin 7-O-β-D-Glucuronide; Formononetin-7-glucuronide; 7-O-Glucuronylformononetin; 4',7-Dihydroxy-3'-methoxyisoflavone 7-glucuronide; Biochanin A metabolite glucuronide (related); Daidzein analog glucuronide; 7-Hydroxy-3-(4-methoxyphenyl)-4-oxo-4H-chromen-7-yl β-D-glucopyranosiduronic acid
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Quality Control

Our Formononetin-7-o-Glucuronide is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, MS), to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical methods is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This compound is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item Specification
Appearance Off-white to yellow powder
Identification (HPLC) Conforms to reference standard
Identification (IR) Conforms to structure
Purity (HPLC) ≥95.0% (Typical: ≥97.0%)
Water Content (KF) ≤5.0%
Residue on Ignition ≤0.5%
Heavy Metals ≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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