Description

(-)-Methoxyphenamine Hydrochloride is a high-purity chiral pharmaceutical intermediate and active pharmaceutical ingredient (API). This compound is valued for its specific stereochemistry, which is critical for targeted pharmacological activity and research into adrenergic agents. It is primarily required by pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and academic institutions engaged in medicinal chemistry and process development. Consistent quality and reliable supply are paramount for its use in advanced synthesis and regulatory filings.

Application

• Pharmaceutical Intermediate: Key chiral building block in the synthesis of specific active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in R&D for studying structure-activity relationships (SAR) of adrenergic compounds.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Process Development: Employed in optimizing synthetic routes and scaling up production for new drug candidates.
• Academic Studies: Utilized in university and institutional research focusing on pharmacology and organic synthesis.

Basic Information

Product Name	(-)-Methoxyphenamine Hydrochloride
CAS No.	18491-42-4
Molecular Formula	C11H17NO • HCl
Molecular Weight	215.72 g/mol
Synonyms	(-)-2-Methoxy-N-methyl-1-phenylpropan-1-amine hydrochloride; (R)-(-)-Methoxyphenamine HCl; Levomethoxyphenamine Hydrochloride; (1R)-1-(2-Methoxyphenyl)-2-(methylamino)propane hydrochloride; L-Methoxyphenamine Hydrochloride; Ritalin intermediate (related); Orthoxine Hydrochloride (stereospecific)
EINECS	Contact for details

Quality Control

Our (-)-Methoxyphenamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets stringent specifications for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.