Description

(E)-3-(4-Nitrophenyl)-1-(Pyridin-3-Yl)Prop-2-En-1-One is a high-purity, synthetic organic compound belonging to the chalcone class, characterized by its distinct conjugated enone system linking a nitrophenyl and a pyridinyl moiety. This compound serves as a versatile and critical building block in advanced chemical synthesis, particularly valued for its role as a key intermediate in pharmaceutical research and material science. It is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for developing new active ingredients and functional materials.

Application

This specialized chalcone derivative is primarily utilized as a sophisticated synthetic intermediate. Its applications are driven by its unique molecular structure, which allows for further functionalization and incorporation into more complex systems.

• Pharmaceutical Intermediate: A key precursor in the research and development of novel drug candidates, particularly for therapeutic areas targeting inflammation, cancer, and central nervous system disorders.
• Agrochemical Synthesis: Used in creating advanced active ingredients for crop protection products, leveraging its structural motifs for biological activity.
• Material Science Research: Serves as a building block for organic electronic materials, such as non-linear optical (NLO) materials and organic light-emitting diodes (OLEDs), due to its electron-accepting nitro group and extended conjugation.
• Chemical Biology Probe: Employed in academic and industrial research to develop molecular probes for studying enzyme interactions and biological pathways.
• Organic Synthesis Scaffold: Utilized in heterocyclic chemistry for the construction of more complex nitrogen-containing ring systems like pyrazolines and isoxazolines.

Basic Information

Product Name	(E)-3-(4-Nitrophenyl)-1-(Pyridin-3-Yl)Prop-2-En-1-One
CAS No.	18451-70-2
Molecular Formula	C14H10N2O3
Molecular Weight	254.24 g/mol
Synonyms	3-(4-Nitrophenyl)-1-(3-pyridinyl)-2-propen-1-one; (E)-1-(3-Pyridinyl)-3-(4-nitrophenyl)-2-propen-1-one; 3'-Pyridyl-4-nitrochalcone; 3-Pyridinyl 4-nitrophenyl ketone; 4-Nitrochalcone derivative; 1-(Pyridin-3-yl)-3-(4-nitrophenyl)prop-2-en-1-one; Chalcone, 3'-pyridyl-4-nitro-; (E)-3-(4-Nitrophenyl)-1-(3-pyridinyl)prop-2-en-1-one
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our fine chemical intermediates. Each batch of (E)-3-(4-Nitrophenyl)-1-(Pyridin-3-Yl)Prop-2-En-1-One is manufactured and analyzed under controlled conditions to ensure consistent purity and identity. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing specific batch results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to protect from moisture and contamination.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.