Description

1,10β-Bis(Methoxycarbonyl)-4Aα,7-Dihydroxy-8-Methylenegibbane-1α-Carboxylic Acid 1,4A-Lactone is a highly functionalized gibbane derivative, a complex diterpenoid lactone of significant interest in advanced organic synthesis and pharmaceutical research. Its intricate molecular architecture makes it a valuable key intermediate for the development of novel bioactive compounds. This product is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the synthesis of complex natural product analogs and specialized chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel diterpenoid-based drug candidates and active pharmaceutical ingredients (APIs).
• Advanced Organic Synthesis: Used as a sophisticated starting material or intermediate for constructing complex molecular frameworks in academic and industrial research.
• Agrochemical Research: Investigated as a precursor for developing new plant growth regulators or bioactive agents with specific modes of action.
• Biochemical Probe Development: Utilized in research to create molecular probes for studying biological pathways and enzyme interactions related to gibberellin signaling.
• Fine Chemical Production: Employed in the manufacture of high-value, low-volume specialty chemicals for niche market applications.

Basic Information

Product Name	1,10β-Bis(Methoxycarbonyl)-4Aα,7-Dihydroxy-8-Methylenegibbane-1α-Carboxylic Acid 1,4A-Lactone
CAS No.	18450-95-8
Molecular Formula	C23H26O8
Molecular Weight	430.45 g/mol
Synonyms	1,10-Bis(methoxycarbonyl)-4aα,7-dihydroxy-8-methylenegibbane-1α-carboxylic acid 1,4a-lactone; 8-Methylenegibberellin A12 methyl ester; Gibberellin A12 methyl ester, 8-methylene-; 1,10-Dicarbomethoxy-8-methylenegibberellin A12 lactone; 8-Methylene GA12 methyl ester; (1α,4aα,7β,10β)-1,10-Bis(methoxycarbonyl)-7-hydroxy-8-methylenegibb-8-ene-1,4a-dicarboxylic acid 1,4a-lactone
EINECS	Contact for details

Quality Control

Our 1,10β-Bis(Methoxycarbonyl)-4Aα,7-Dihydroxy-8-Methylenegibbane-1α-Carboxylic Acid 1,4A-Lactone is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization, including HPLC for purity assay, NMR, and MS for structural confirmation. Our products are suitable for research and development applications requiring reliable and well-defined chemical intermediates. Certificates of Analysis (COA) detailing all relevant specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.