Description

Methyl [3S-(3Alpha,3Aalpha,6Alpha,8Aalpha)]-Octahydro-7,7-Dimethyl-8-Methylene-1H-3A,6-Methanoazulene-3-Carboxylate is a high-purity, stereochemically defined synthetic intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a key chiral building block in the construction of complex molecular architectures, particularly in the pharmaceutical sector. It is primarily needed by R&D chemists and process development scientists in the fine chemical, agrochemical, and fragrance industries seeking to introduce specific structural motifs with high stereochemical fidelity.

Application

• Pharmaceutical Intermediate: Serves as a crucial chiral precursor in the synthesis of active pharmaceutical ingredients (APIs) with complex polycyclic or terpenoid-like structures.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, where its rigid, functionalized core can contribute to biological activity.
• Fragrance & Flavor Chemistry: Acts as a starting material for the synthesis of high-value aroma chemicals and synthetic musk compounds due to its methanoazulene skeleton.
• Material Science Research: Investigated as a monomer or functional additive in the development of specialized polymers with unique optical or mechanical properties.
• Academic & Institutional Research: Employed in methodological studies and total synthesis projects within university and government laboratories.
• Catalyst Ligand Development: Its structure can be modified to create novel chiral ligands for asymmetric catalysis.

Basic Information

Product Name	Methyl [3S-(3Alpha,3Aalpha,6Alpha,8Aalpha)]-Octahydro-7,7-Dimethyl-8-Methylene-1H-3A,6-Methanoazulene-3-Carboxylate
CAS No.	18444-89-8
Molecular Formula	C17H24O2
Molecular Weight	260.37 g/mol
Synonyms	Methyl (1S,3aS,4R,6aR)-1,2,3,3a,4,5,6,6a-Octahydro-4,7,7-trimethyl-1-methylene-1H-cyclopenta[1,3]cyclopropa[1,2]benzene-4-carboxylate; Methyl (1S,3aS,4R,6aR)-4,7,7-Trimethyl-1-methyleneoctahydro-1H-cyclopenta[1,3]cyclopropa[1,2]benzene-4-carboxylate; (1S,3aS,4R,6aR)-4,7,7-Trimethyl-1-methyleneoctahydro-1H-cyclopenta[1,3]cyclopropa[1,2]benzene-4-carboxylic acid methyl ester; A derivative of Longifolene.
EINECS	Contact for details

Quality Control

Our Methyl [3S-(3Alpha,3Aalpha,6Alpha,8Aalpha)]-Octahydro-7,7-Dimethyl-8-Methylene-1H-3A,6-Methanoazulene-3-Carboxylate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to preserve optimal quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.