Description

1-Trimethylsiloxy-4-Trimethylsiloxymethylbenzene is a specialized organosilicon compound featuring two trimethylsilyl protecting groups. This chemical is valued for its role as a versatile synthetic intermediate and protecting group reagent in advanced organic synthesis. It is primarily sought after by research and development laboratories and chemical manufacturers in the pharmaceutical, agrochemical, and materials science sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly where protection of phenolic or benzylic hydroxyl groups is required.
• Agrochemical Synthesis: Serves as a key building block in the production of advanced pesticides and herbicides.
• Material Science Precursor: Employed in the development of specialty polymers, silicone hybrids, and advanced organic electronic materials.
• Organic Synthesis Reagent: Acts as a silylating agent to introduce trimethylsilyl (TMS) protecting groups, enhancing solubility and stability of intermediates.
• Liquid Crystal & OLED Research: Utilized as a precursor or modifying agent in the synthesis of liquid crystal compounds and organic light-emitting diode (OLED) materials.
• Cross-Coupling Reactions: Functions as a substrate or reagent in palladium-catalyzed cross-coupling reactions, such as Suzuki or Heck reactions.

Basic Information

Product Name	1-Trimethylsiloxy-4-Trimethylsiloxymethylbenzene
CAS No.	18401-58-6
Molecular Formula	C13H24O2Si2
Molecular Weight	268.50 g/mol
Synonyms	1,4-Bis(trimethylsiloxymethyl)benzene; Benzene-1,4-bis(methyleneoxytrimethylsilane); p-Bis(trimethylsiloxymethyl)benzene; 1,4-Bis[(trimethylsilyloxy)methyl]benzene; α,α'-Bis(trimethylsiloxy)-p-xylene; p-Xylylene bis(trimethylsilyl ether); TMS-protected p-xylylene glycol; 1,4-Bis(trimethylsilyloxymethyl)benzene
EINECS	Contact for details

Quality Control

Our 1-Trimethylsiloxy-4-Trimethylsiloxymethylbenzene is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We can support development projects requiring compliance with ICH guidelines or other regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). The compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.