Description

2H-Pyran-3-Carbonyl Chloride, 2-Oxo- (8Ci,9Ci) CAS NO 18398-80-6 is a highly reactive acid chloride derivative of a pyranone, serving as a critical building block in advanced organic synthesis. Its value lies in its ability to efficiently introduce the 2-oxo-2H-pyran-3-carbonyl moiety, enabling the construction of complex heterocyclic and pharmaceutical intermediates. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those containing fused heterocyclic systems.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with complex molecular architectures.
• Material Science: Building block for creating specialized polymers, ligands, and organic electronic materials.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry and the exploration of new chemical spaces.
• Peptide Mimetics: Employed in the design and synthesis of peptidomimetics and other bioactive molecules.
• Dye & Pigment Chemistry: Intermediate for the production of specialized dyes and functional chromophores.

Basic Information

Product Name	2H-Pyran-3-Carbonyl Chloride, 2-Oxo- (8Ci,9Ci)
CAS No.	18398-80-6
Molecular Formula	C6H3ClO3
Molecular Weight	158.54 g/mol
Synonyms	2-Oxo-2H-pyran-3-carbonyl chloride; 3-Pyrancarbonyl chloride, 2-oxo-; 2-Oxo-2H-pyran-3-carboxylic acid chloride; 2H-Pyran-3-carbonyl chloride, 2-oxo-; 3-Carboxy-2-pyrone chloride; 2-Oxo-2H-pyran-3-carbonylchloride; 18398-80-6; 2-Oxopyran-3-carbonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 2H-Pyran-3-Carbonyl Chloride, 2-Oxo- undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency, meeting the stringent requirements of research and process chemistry. Our quality assurance protocols are designed to support cGMP and ISO standards where applicable. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from strong bases, oxidizers, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area %)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.