Description

1-Propanol, 3-(Trimethylsilyl)-, Acetate is a specialized organosilicon compound that serves as a versatile reagent and protecting group intermediate in advanced synthetic chemistry. Its value lies in its ability to introduce the trimethylsilyl (TMS) group, a key functionality for modifying reactivity and solubility in target molecules. This product is essential for researchers and process chemists in the pharmaceutical, agrochemical, and material science industries who require high-purity intermediates for complex synthesis.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) where silyl protection of hydroxyl groups is required.
• Agrochemical Synthesis: Serves as a key building block in the production of advanced pesticides and herbicides.
• Material Science Precursor: Employed in the development of silicone-based polymers and advanced functional materials.
• Organic Synthesis Reagent: Acts as a silylating agent in laboratory-scale and pilot-scale reactions to protect alcohols.
• Flavor and Fragrance Industry: Utilized in the synthesis of specific aroma chemicals requiring siloxane linkages.
• Cross-Coupling Reactions: Functions as a reactant in palladium-catalyzed and other metal-mediated coupling processes.

Basic Information

Product Name	1-Propanol, 3-(Trimethylsilyl)-, Acetate
CAS No.	18388-41-5
Molecular Formula	C8H18O2Si
Molecular Weight	174.31 g/mol
Synonyms	3-(Trimethylsilyl)propyl acetate; (3-Acetoxypropyl)trimethylsilane; Trimethylsilylpropyl acetate; 3-Acetoxypropyltrimethylsilane; 3-(Trimethylsilyl)-1-propanol acetate; Acetic acid 3-(trimethylsilyl)propyl ester; 1-Propanol, 3-(trimethylsilyl)-, 1-acetate
EINECS	242-246-5

Quality Control

Our production of 1-Propanol, 3-(Trimethylsilyl)-, Acetate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including GC, HPLC, and NMR to verify identity and assay. A comprehensive Certificate of Analysis (COA) detailing purity, specific impurities, and physical properties is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to prevent moisture absorption and maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20/D)	1.410 - 1.420
Density (20°C)	0.88 - 0.92 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.