Description

1-(Trimethylsilyl)-1-Pentyn-3-One is a specialized organosilicon building block featuring both a silyl-protected alkyne and a ketone functional group. This unique bifunctional structure makes it a versatile intermediate for advanced organic synthesis, particularly in the construction of complex molecular architectures. It is primarily utilized by pharmaceutical researchers and fine chemical manufacturers for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the synthesis of complex drug candidates, especially those requiring alkyne or ketone functional group manipulation.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products.
• Material Science: Building block for synthesizing specialized polymers, dendrimers, or silicon-containing advanced materials.
• Organic Synthesis: Versatile reagent for cross-coupling reactions, nucleophilic additions, and the preparation of heterocyclic compounds.
• Ligand & Catalyst Development: Precursor for creating novel ligands and organometallic catalysts used in asymmetric synthesis.
• Academic & R&D: Valuable tool in research laboratories for methodological studies and exploring new synthetic pathways.

Basic Information

Product Name	1-(Trimethylsilyl)-1-Pentyn-3-One
CAS No.	18387-58-1
Molecular Formula	C8H14OSi
Molecular Weight	154.28 g/mol
Synonyms	1-Pentyn-3-one, 1-(trimethylsilyl)-; 1-Trimethylsilyl-1-pentyn-3-one; 3-Oxo-1-(trimethylsilyl)-1-pentyne; 1-(Trimethylsilyl)pent-1-yn-3-one; TMS-protected pentynone; Trimethyl(3-oxopent-1-yn-1-yl)silane
EINECS	Contact for details

Quality Control

Our 1-(Trimethylsilyl)-1-Pentyn-3-One is produced under stringent quality management protocols. Each batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at room temperature (15-25°C). Due to its highly volatile and light-sensitive nature, containers must be kept tightly sealed and away from heat sources and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.